Age‐specific progression of nigrostriatal dysfunction in Parkinson's disease
Identifieur interne : 001891 ( Main/Exploration ); précédent : 001890; suivant : 001892Age‐specific progression of nigrostriatal dysfunction in Parkinson's disease
Auteurs : Raúl De La Fuente-Fernández [Canada] ; Michael Schulzer [Canada] ; Lisa Kuramoto [Canada] ; Jacquelyn Cragg [Canada] ; Nandhagopal Ramachandiran [Canada] ; Wing L. Au [Canada] ; Edwin Mak [Canada] ; Jess Mckenzie [Canada] ; Siobhan Mccormick [Canada] ; Vesna Sossi [Canada] ; Thomas J. Ruth [Canada] ; Chong S. Lee [Canada] ; Donald B. Calne [Canada] ; A. Jon Stoessl [Canada]Source :
- Annals of Neurology [ 0364-5134 ] ; 2011-05.
English descriptors
- KwdEn :
- Adult, Aged, Aging, Carbon Isotopes, Corpus Striatum (physiopathology), Disease Progression, Female, Fluorodeoxyglucose F18, Humans, Longitudinal Studies, Male, Methylphenidate, Middle Aged, Parkinson Disease (diagnostic imaging), Parkinson Disease (pathology), Positron-Emission Tomography (methods), Protein Binding (physiology), Substantia Nigra (diagnostic imaging), Substantia Nigra (physiopathology), Tetrabenazine (analogs & derivatives), Tritium, Young Adult.
- MESH :
- chemical , analogs & derivatives : Tetrabenazine.
- chemical : Carbon Isotopes, Fluorodeoxyglucose F18, Methylphenidate, Tritium.
- diagnostic imaging : Parkinson Disease, Substantia Nigra.
- methods : Positron-Emission Tomography.
- pathology : Parkinson Disease.
- physiology : Protein Binding.
- physiopathology : Corpus Striatum, Substantia Nigra.
- Adult, Aged, Aging, Disease Progression, Female, Humans, Longitudinal Studies, Male, Middle Aged, Young Adult.
Abstract
To investigate in vivo the impact of age on nigrostriatal dopamine dysfunction in Parkinson's disease (PD).
Url:
DOI: 10.1002/ana.22284
Affiliations:
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Le document en format XML
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
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<term>Corpus Striatum (physiopathology)</term>
<term>Disease Progression</term>
<term>Female</term>
<term>Fluorodeoxyglucose F18</term>
<term>Humans</term>
<term>Longitudinal Studies</term>
<term>Male</term>
<term>Methylphenidate</term>
<term>Middle Aged</term>
<term>Parkinson Disease (diagnostic imaging)</term>
<term>Parkinson Disease (pathology)</term>
<term>Positron-Emission Tomography (methods)</term>
<term>Protein Binding (physiology)</term>
<term>Substantia Nigra (diagnostic imaging)</term>
<term>Substantia Nigra (physiopathology)</term>
<term>Tetrabenazine (analogs & derivatives)</term>
<term>Tritium</term>
<term>Young Adult</term>
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<term>Fluorodeoxyglucose F18</term>
<term>Methylphenidate</term>
<term>Tritium</term>
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<keywords scheme="MESH" qualifier="diagnostic imaging" xml:lang="en"><term>Parkinson Disease</term>
<term>Substantia Nigra</term>
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<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Positron-Emission Tomography</term>
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<keywords scheme="MESH" qualifier="pathology" xml:lang="en"><term>Parkinson Disease</term>
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<term>Substantia Nigra</term>
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<term>Aged</term>
<term>Aging</term>
<term>Disease Progression</term>
<term>Female</term>
<term>Humans</term>
<term>Longitudinal Studies</term>
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<front><div type="abstract">To investigate in vivo the impact of age on nigrostriatal dopamine dysfunction in Parkinson's disease (PD).</div>
</front>
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<affiliations><list><country><li>Canada</li>
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<name sortKey="Au, Wing L" sort="Au, Wing L" uniqKey="Au W" first="Wing L." last="Au">Wing L. Au</name>
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<name sortKey="De La Fuente Ernandez, Raul" sort="De La Fuente Ernandez, Raul" uniqKey="De La Fuente Ernandez R" first="Raúl" last="De La Fuente-Fernández">Raúl De La Fuente-Fernández</name>
<name sortKey="Kuramoto, Lisa" sort="Kuramoto, Lisa" uniqKey="Kuramoto L" first="Lisa" last="Kuramoto">Lisa Kuramoto</name>
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<name sortKey="Mak, Edwin" sort="Mak, Edwin" uniqKey="Mak E" first="Edwin" last="Mak">Edwin Mak</name>
<name sortKey="Mccormick, Siobhan" sort="Mccormick, Siobhan" uniqKey="Mccormick S" first="Siobhan" last="Mccormick">Siobhan Mccormick</name>
<name sortKey="Mckenzie, Jess" sort="Mckenzie, Jess" uniqKey="Mckenzie J" first="Jess" last="Mckenzie">Jess Mckenzie</name>
<name sortKey="Ramachandiran, Nandhagopal" sort="Ramachandiran, Nandhagopal" uniqKey="Ramachandiran N" first="Nandhagopal" last="Ramachandiran">Nandhagopal Ramachandiran</name>
<name sortKey="Ruth, Thomas J" sort="Ruth, Thomas J" uniqKey="Ruth T" first="Thomas J." last="Ruth">Thomas J. Ruth</name>
<name sortKey="Schulzer, Michael" sort="Schulzer, Michael" uniqKey="Schulzer M" first="Michael" last="Schulzer">Michael Schulzer</name>
<name sortKey="Sossi, Vesna" sort="Sossi, Vesna" uniqKey="Sossi V" first="Vesna" last="Sossi">Vesna Sossi</name>
<name sortKey="Stoessl, A Jon" sort="Stoessl, A Jon" uniqKey="Stoessl A" first="A. Jon" last="Stoessl">A. Jon Stoessl</name>
</country>
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